How long does it take for weed edibles to kick in? The amount of time it takes for the effects of edibles to kick in varies and also depends on your metabolism. People with faster metabolisms may feel effects after an hour; people with slower metabolisms may not feel the effects for two hours or more. An important factor is whether you consume the edible on an empty stomach or after you've eaten. An empty stomach will feel the effects much more quickly — a full stomach will keep it from hitting you as hard.